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Mecbotamab - CAS 2460400-28-4
Mecbotamab - CAS 2460400-28-4
SKU:MF-0099852-01
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Product Details
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Bioactivity
Mecbotamab vedotin (BA3011) is a humanized IgG1-κ antibody engineered to target the AXL receptor tyrosine kinase (AXL) . Serving as a conditionally active biologic (CAB), mecbotamab is conjugated to monomethyl auristatin E (MMAE) through a cleavable linker, creating an antibody-drug conjugate (ADC) for therapeutic use [1] [2].
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Target
ADC Antibody, TAM Receptor
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Related Pathways
Antibody-drug Conjugate/ADC Related, Tyrosine Kinase/Adaptors
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CAS Number
2460368
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Inhibitory Antibodies