Meclizine - CAS 569-65-3

Meclizine, also known as Meclozine, is a piperazine class H1 antagonist with antihistamine properties that inhibits the interaction of histamine at H1 receptors reversibly. It serves as an effective anti-motion sickness agent, able to cross the blood-brain barrier. Additionally, Meclizine acts as an agonist ligand for the mouse constitutive androstane receptor (CAR) and an inverse agonist for human CAR, making it useful in research on polyQ toxicity disorders, including Huntington's disease.

Apoptosis, Histamine Receptor

GPCR/G Protein, Apoptosis, Immunology/Inflammation, Neuroscience

501

0.9955

C25H27ClN2

390.95

Cc1cccc(CN2CCN(CC2)C(c2ccccc2)c2ccc(Cl)cc2)c1

-20°C

Ice Packs

Small Compound