MED6-189 - CAS 2650073-66-6

MED6-189, an analog of kalihinol, disrupts the apicoplast functions and vesicular transport in the malignant malaria parasite (P. falciparum, IC50 < 50 nM) . The compound specifically targets the apicoplast, which is a non-photosynthetic plastid essential for isoprenoid synthesis, found in most apicomplexan parasites.

Parasite

Microbiology/Virology

2650001

C17H26N2O

274.4

C(C)(C)[C@@H]1[C@@]2([C@@]([C@](C#N)(C)CC1)(CC[C@](C#N)(C)[C@@H]2O)[H])[H]

-20°C

Ice Packs

Small Compound