MeIQx - CAS 77500-04-0

MeIQx (MeIQx) is a food-derived carcinogen that has been found in high temperature-cooked fish and meats.1It is activated by hydroxylation and subsequent O-acetylationviathe cytochrome P450 (CYP) isoform CYP1A2 and N-acetyltransferase 2, respectively, in UV5 cells expressing the human enzymes to a metabolite that reacts with DNA to form adducts.2MeIQx (200 and 400 ppm in the diet) induces tumor formation in rats.3

Cytochromes P450, Others

Metabolism, Others

77500-04-0

C11H11N5

213.244

Cc1cnc2ccc3n(C)c(N)nc3c2n1

-20°C

Ice Packs

Small Compound