Melicopine - CAS 568-01-4

Melicopine is an alkaloid found in Z. simulans, known for its antimalarial and anticancer properties. It inhibits P. falciparum strains, including chloroquine-sensitive 3D7 (IC50 of 29.7 μg/mL) and chloroquine-resistant Dd2 (IC50 of 33.7 μg/mL) . Additionally, Melicopine exhibits cytotoxicity against prostate cancer cells PC-3M (IC50 of 47.9 μg/mL) and LNCaP (IC50 of 37.8 μg/mL), but it is inactive in non-cancerous HEK293 cells (IC50 greater than 100 μg/mL) . Melicopine holds potential for research in anticancer and anti-infective applications.

Parasite

Microbiology/Virology

0568-01-04

C17H15NO5

313.31

O=C1C=2C=CC=CC2N(C3=C4OCOC4=C(OC)C(OC)=C13)C

-20°C

Ice Packs

Natural Product