Melittin free acid - CAS 123168-46-7

Melittin free acid, a basic 26-amino-acid polypeptide, constitutes the primary active component of honeybee venom and serves as a phospholipase A2 (PLA2) activator. Exhibiting a broad-spectrum antifungal effect, it presents MIC values ranging from 0.4-60 μM. Its mechanism includes inducing cell apoptosis, inhibiting (1,3) -β-D-glucan synthase, and engaging in multiple pathways [1] [2].

Antifungal, Apoptosis, Phospholipase, Reactive Oxygen Species

NF-κB, Metabolism, Apoptosis, Microbiology/Virology, Immunology/Inflammation

123115

C131H228N38O32

2847.45

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-20°C

Ice Packs

Peptide