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Molfinity

MELK-8a - CAS 1922153-17-0

MELK-8a - CAS 1922153-17-0

MF-0138751-01

$1,383.80 USD
$1,383.80 USD
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Product Details

  • Bioactivity

    MELK-8a (NVS-MELK8a) is a potent and selective inhibitor of maternal embryonic leucine zipper kinase (MELK), with an IC50 of 2 nM and an IC50 of 0.42 μM in cellular assays. MELK is crucial in regulating mitosis in cancer cells.

  • Target

    Haspin Kinase, Others, PDGFR, MELK

  • Related Pathways

    Cell Cycle/Checkpoint, Tyrosine Kinase/Adaptors, PI3K/Akt/mTOR signaling, Angiogenesis, Others

  • CAS Number

    1922136

  • Molecular Formula

    C25H32N6O

  • Molecular Weight

    432.56

  • SMILES

    O(CC1CCNCC1)C=2C(=CC=NC2)C3=CN(N=C3)C4=CC=C(C=C4)N5CCN(C)CC5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound