Menin-MLL inhibitor 31 - CAS 2863656-86-2

Menin-MLL inhibitor 31 (compound 18) effectively disrupts the menin-MLL interaction, demonstrating a potent IC 50 value of 4.6 nM [1].

Epigenetic Reader Domain

Chromatin/Epigenetic

2863656-86-2

C77H119FN28O14

1679.95

O=C1C2(NC(=O)[C@]3(N(C(=O)[C@H](CC4=CC(F)=CC=C4)NC(=O)[C@@H](NC([C@H](CC=5C=6C(NC5)=CC=CC6)NC([C@@H](NC([C@@H](NC(C)=O)C)=O)CCCNC(=N)N)=O)=O)CCCC[C@@H](C(=O)N7C[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCN)=O)CC7)N1)CCC3)[H])CCC2

-20°C

Ice Packs

Peptide