Mensacarcin - CAS 808750-39-2

Mensacarcin, a highly complex polyketide compound, exhibits multifaceted effects on cellular processes. Specifically, it targets mitochondria, perturbs energy metabolism within these organelles, and activates caspase-dependent apoptotic pathways. Functionally, Mensacarcin can serve as a cytotoxic constituent in antibody-drug conjugates (ADCs) . Furthermore, this antibiotic compound displays broad-spectrum inhibition of cell growth across various cancer cell lines and demonstrates potent induction of apoptosis in melanoma cells.

Mitochondrial Metabolism, ADC Cytotoxin, Apoptosis

Antibody-drug Conjugate/ADC Related, Apoptosis, Metabolism

808709

C21H24O9

420.41

O(C)[C@@H]1[C@@]23[C@](O2)(C(=O)C=4C1=C(OC)C=CC4)[C@H](O)[C@H](C)[C@](C(=O)[C@H]5[C@H](C)O5)(O)[C@@H]3O

-20°C

Ice Packs

Small Compound