MeOIstPyrd - CAS 2308548-54-9

MeOIstPyrd is an anti-skin cancer agent that inhibits cell proliferation, migration, and spheroid formation by activating the mitochondrial intrinsic apoptotic pathway. It induces DNA damage, activates p53, increases its half-life, and stabilizes p53 via ser15 phosphorylation. Additionally, MeOIstPyrd interfaces with MDM2 within the p53 sub-pocket, preventing the p53-MDM2 interaction [1].

Others, MDM-2/p53

Others, Apoptosis

2308485

C14H16N4O2S

304.37

N(\NC(=S)N1CCCC1)=C\2/C=3C(NC2=O)=CC=C(OC)C3

-20°C

Ice Packs

Small Compound