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Merestinib dihydrochloride - CAS 1206801-37-7

Merestinib dihydrochloride - CAS 1206801-37-7

MF-0016990-01

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Product Details

  • Bioactivity

    Merestinib dihydrochloride (LY2801653 dihydrochloride) is an orally available kinase inhibitor with antitumor activity that inhibits MET, AXL, RON, and MKNK1/2, and inhibits the growth of NTRK fusion-carrying tumors.

  • Target

    Discoidin Domain Receptor (DDR), c-Met/HGFR, ROS Kinase, FLT, TAM Receptor, Tyrosine Kinases

  • Related Pathways

    Angiogenesis, Tyrosine Kinase/Adaptors

  • CAS Number

    1206757

  • Molecular Formula

    C30H24Cl2F2N6O3

  • Molecular Weight

    625.45

  • SMILES

    Cc1ccc(C(=O)Nc2ccc(Oc3cc4cnn(C)c4cc3-c3cn[nH]c3)c(F)c2)c(=O)n1-c1ccc(F)cc1.Cl.Cl

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound