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MerTK-IN-3 - CAS 3029898-85-6
MerTK-IN-3 - CAS 3029898-85-6
SKU:MF-0118298-01
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Product Details
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Bioactivity
MerTK-IN-3 (compound 11) is an orally active, selective inhibitor of MerTK, exhibiting IC50 values of 21.5 nM for MerTK and 991.3 nM for Tyro3. It is applicable in colon cancer research.
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Target
TAM Receptor
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Related Pathways
Tyrosine Kinase/Adaptors
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CAS Number
3029807
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Molecular Formula
C36H31FN8O4
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Molecular Weight
658.68
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SMILES
O=C(NC1=CC=C(OC=2N=CN=C3OC(C=4C=NN(C4)C)=C(C5=CC=CC(=C5)CN(C)C)C23)C=C1)C6=CN(N(C6=O)C7=CC=C(F)C=C7)C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound