Mesembrine - CAS 468-53-1

Mesembrine ((+) -Mesembrine), a primary alkaloid distinguished by its aryloctahydroindole structure, acts as a potent 5-HT transporter inhibitor with an inhibition constant (K i) of 1.4 nM. Additionally, it demonstrates inhibitory activity against phosphodiesterase 4B (PDE4B) with an inhibitory concentration 50% (IC50) of 7.8 μM [1] [2].

5-HT Receptor, Others, PDE

Metabolism, Others, GPCR/G Protein, Neuroscience

414

C17H23NO3

289.37

[H][C@@]12CC(=O)CC[C@@]1(CCN2C)c1ccc(OC)c(OC)c1

-20°C

Ice Packs

Natural Product