Metahexestrol - CAS 71953-72-5

Metahexestrol is an inhibitor of the estrogen receptor (E2R) with antitumor activity. It significantly inhibits the proliferation of estrogen receptor-positive MCF-7 human breast cancer cell line with an ED50 of 1.0 μM. Additionally, Metahexestrol shows inhibitory activity in estrogen receptor-negative MDA-MB-231 cell lines, and its antiproliferative effect is not reversed by estrogen, suggesting that its mechanism may be partially independent of the E2R pathway. Metahexestrol is applicable in research on estrogen-dependent breast cancer.

Estrogen Receptor/ERR

Endocrinology/Hormones

71876

C18H22O2

270.366

[C@H]([C@H](CC)C1=CC(O)=CC=C1)(CC)C2=CC(O)=CC=C2

-20°C

Ice Packs

Small Compound