Metallo-β-lactamase-IN-5 - CAS 1417737-65-5

Metallo-β-lactamase-IN-5 (compound 5c) is a potent inhibitor of metallo-β-lactamases (MBLs), demonstrating inhibitory activity against MBLs NDM-1 and VIM-1. It effectively inhibits HUVECs with an IC50 value of 45 μg/mL. Additionally, when combined with Imipenem, Metallo-β-lactamase-IN-5 exhibits synergistic antimicrobial activity [1].

Others, Apoptosis, Antibacterial

Apoptosis, Others, Microbiology/Virology

1417667

C19H16N4O3

348.36

N(=O)(=O)C=1C2=C(C(O)=C(CN(CC3=CC=CC=C3)CC#N)C1)N=CC=C2

-20°C

Ice Packs

Small Compound