Metallo-β-lactamase-IN-6 - CAS 1439899-44-1

Metallo-β-lactamase-IN-6 is a highly effective inhibitor of VIM-Type metallo-β-lactamase, demonstrating IC50 values of 0.56 μM, 29.50 μM, and 5.78 μM for VIM-2, VIM-1, and VIM-5, respectively. Additionally, Metallo-β-lactamase-IN-6 exhibits potent synergistic antibacterial properties when combined with Meropenem, particularly against engineered Escherichia coli strains and clinically isolated Pseudomonas aeruginosa carrying the VIM-2 MBL gene [1].

Antibacterial, Others

Others, Microbiology/Virology

1439854

C10H9N3O2

203.2

OC(=O)c1nccn1Cc1ccncc1

-20°C

Ice Packs

Small Compound