Methotrexate - CAS 59-05-2

Methotrexate (WR19039) is a folate analog, an inhibitor of the dihydrofolate reductase DHFR. Methotrexate has antimetabolic, antitumor, and immunosuppressive activities, and is commonly used in rheumatoid arthritis and various tumors.

ADC Cytotoxin, Dehydrogenase, Apoptosis, DNA/RNA Synthesis, Antifolate

Antibody-drug Conjugate/ADC Related, Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Metabolism, Apoptosis

59-05-2

0.9991

C20H22N8O5

454.44

NC=1C2=C(N=CC(CN(C)C3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)N=C(N)N1

-20°C

Ice Packs

Small Compound