Methotrexate α-tert-butyl ester - CAS 79640-70-3

Methotrexate α-tert-butyl ester is a protected analog of the antineoplastic and immunosuppressive drug methotrexate (MTX), in which the β-carboxyl group of the L-glutamate moiety is esterified with a tert-butyl group. Methotrexate α-tert-butyl ester is primarily used in chemical synthesis and prodrug development studies.

Others, DNA/RNA Synthesis, Antifolate

DNA Damage/DNA Repair, Others, Cell Cycle/Checkpoint

79567

0.86865

NC=1C2=C(N=C(N)N1)N=CC(CN(C)C3=CC=C(C(N[C@H](C(OC(C)(C)C)=O)CCC(O)=O)=O)C=C3)=N2

-20°C

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