Methyl Diethyldithiocarbamate - CAS 686-07-7

Methyl diethyldithiocarbamate is an active metabolite of the aldehyde dehydrogenase inhibitor disulfiram .1It is produced by methylation of the disulfiram metabolite diethyldithiocarbamate in mouse liver microsomes.2Methyl diethyldithiocarbamate inhibits liver low Kmaldehyde dehydrogenase (ALDH) in rats (ID50= 15.5 mg/kg) .1It decreases mean arterial pressure (MAP) and increases heart rate during ethanol challenge in rats when administered at a dose of 20.6 mg/kg.

Others, Dehydrogenase

Metabolism, Others

686-07-7

C6H13NS2

163.3

S=C(SC)N(CC)CC

-20°C

Ice Packs

Small Compound