Methylbenzoprim - CAS 118344-71-1

Methylbenzoprim is an innovative multifunctional thymidylate synthase (TYMS) inhibitor. It exhibits greater antitumor activity compared to current fluoropyrimidines and antifolates, without inducing TYMS overexpression. In pancreatic xenograft tumor models and hTS/Ink4a/Arf null genetically engineered mouse models, Methylbenzoprim effectively prolongs survival.

118272

C20H22N6O2

378.43

CN(CC1=CC=CC=C1)C2=CC=C(C3=C(CC)N=C(N)N=C3N)C=C2[N+]([O-])=O

-20°C

Ice Packs

Small Compound