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Methylspinazarin - CAS 41768-12-1

Methylspinazarin - CAS 41768-12-1

SKU:MF-0050564

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  • Bioactivity

    Methylspinazarin is a naphthoquinone bacterial metabolite that has been found in Streptomyces and is an inhibitor of catechol O-methyltransferase (COMT; IC50 = 0.8 μg/ml) .1 It is selective for COMT over tyrosine hydroxylase, DOPA decarboxylase, and dopamine-β-hydroxylase at 100 μg/ml. Methylspinazarin decreases blood pressure in spontaneously hypertensive rats when administered at a dose of 50 mg/kg.

  • Target

    Others, Transferase

  • Related Pathways

    Others, Metabolism

  • CAS Number

    41755

  • Molecular Formula

    C11H8O6

  • Molecular Weight

    236.18

  • SMILES

    Cc1cc(O)c2C(=O)C(O)=C(O)C(=O)c2c1O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound