MF-DH-300 - CAS 2673403-86-4

MF-DH-300 is a 15-PGDH inhibitor with an IC50 of 1.6 nM. It blocks the interaction between 15-PGDH and PGE2, promoting stem cell proliferation, increasing muscle strength, and enhancing mitochondrial function. Additionally, MF-DH-300 raises the expression of survival motor neuron (SMN) protein and is applicable in research on muscle diseases such as spinal muscular atrophy (SMA) .

Dehydrogenase

Metabolism

2673313

C20H18N4O

330.38

N#CC1=CC=CC(=C1)N2C=CC=3C=C(C=NC32)C(=O)N4CCCCC4

-20°C

Ice Packs

Small Compound