MG-132 - CAS 133407-82-6

MG-132 (Z-Leu-Leu-Leu-al) is a 26S proteasome inhibitor (IC50=100 nM) that is cell-permeable and reversible. MG-132 acts as an autophagy activator and also induces apoptosis.

Apoptosis, Proteasome, Autophagy

Apoptosis, Autophagy, Ubiquitination, Proteases/Proteasome

133407-82-6

0.9999

C26H41N3O5

475.62

CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C=O

-20°C

Ice Packs

Small Compound