MGluR2 modulator 5 - CAS 1639898-35-3

MGluR2 modulator5 (Compound 11) is a selective negative allosteric modulator with oral activity, exhibiting an IC50 of 8.9 nM. Pharmacokinetic studies in rats have demonstrated its effective penetration through the blood-brain barrier. This compound is utilized in research related to cognitive and neurological functions in mood disorders, contributing to the field of neurological diseases.

GluR

Neuroscience

1639860

C20H17F3N4O

386.37

O=C1C2=C(C=NN2[C@@H](C)CN1C3=CC=C(C(F)(F)F)C=C3)C=4C=C(C)N=CC4

-20°C

Ice Packs

Small Compound