MGS-0039 - CAS 569686-87-9

MGS-0039 is a group II metabotropic glutamate receptor (mgluR2/3) antagonist. Antidepressant-like action of group II mGlu receptor antagonists does not depend on serotonergic system activation. However, the AMPA receptor seems to play a key role in the antidepressant-like action of these compounds. Dopamine release in the NAc shell is regulated by mGlu 2/3 receptors.

GluR, Others

Neuroscience, Others

569590

C15H14Cl2FNO5

378.18

C(O)(=O)[C@]1(F)[C@@]2([C@]1(C[C@@H](OCC3=CC(Cl)=C(Cl)C=C3)[C@]2(C(O)=O)N)[H])[H]

-20°C

Ice Packs

Small Compound