MHTT-IN-1 - CAS 2839311-21-4

MHTT-IN-1 (Example 1) is a potent inhibitor of the mutant huntingtin protein (mHTT), which is primarily responsible for Huntington's disease (HD), an inherited autosomal dominant neurodegenerative disorder. This compound effectively reduces mHTT levels with an EC50 of 46 nM.

Huntingtin, Others

Others, Neuroscience

2839286

C18H19N7OS

381.45

O=C1C=C(N=C2SC(=CN12)N3CCNCC3)C4=NN5C=C(N=C5C(=C4)C)C

-20°C

Ice Packs

Small Compound