MI-192 - CAS 1415340-63-4

MI-192 is a selective HDAC2 and HDAC3 inhibitor with IC50 values of 30 nM and 16 nM, respectively. It exhibits greater selectivity for HDAC2/3 over other HDAC isomers and induces apoptosis in myeloid leukemic cells, indicating potential therapeutic use in leukemia and as an anti-stroke agent [1] [2].

Others, Apoptosis, HDAC

Apoptosis, Chromatin/Epigenetic, Others, DNA Damage/DNA Repair

1415273

C24H21N3O2

383.44

O=C1C=2C(C(=C)CN1CC3=CC=C(C(NC4=C(N)C=CC=C4)=O)C=C3)=CC=CC2

-20°C

Ice Packs

Small Compound