Midostaurin - CAS 120685-11-2

PKC412 (Midostaurin (PKC412) ; CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platelet-derived growth factor receptor (PDGFR) and FMS-like tyrosine kinase 3 (FLT3) tyrosine kinases, which may result in disruption of the cell cycle, inhibition of proliferation, apoptosis, and inhibition of angiogenesis in susceptible tumors.

PKC, c-Kit, VEGFR, Apoptosis, NO Synthase

Cytoskeletal Signaling, Angiogenesis, Apoptosis, Chromatin/Epigenetic, Immunology/Inflammation, Tyrosine Kinase/Adaptors

120685-11-2

>99.99%

C35H30N4O4

570.64

COC1C(CC2OC1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1

-20°C

Ice Packs

Small Compound