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Milademetan free base - CAS 1398569-75-9
Milademetan free base - CAS 1398569-75-9
SKU:MF-0050806-01
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$3,226.55 USD
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$3,226.55 USD
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Product Details
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Bioactivity
Milademetan (DS-3032b or DS-3032) is a potent and selective MDM2 inhibitor with potential antineoplastic activity. Milademetan (p.o.) binds to and prevents the binding of MDM2 protein to the transcriptional activation domain of the tumor suppressor protein p53.
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Target
Others, MDM-2/p53
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Related Pathways
Apoptosis, Others
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CAS Number
1398485
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Molecular Formula
C37H42Cl2FN5O7S
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Molecular Weight
790.73
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SMILES
Cc1ccc(cc1)S(O)(=O)=O.CC1(C)CCC2(CC1)N[C@H]([C@H](c1ccnc(Cl)c1F)[C@]21C(=O)Nc2cc(Cl)ccc12)C(=O)N[C@@H]1CC[C@H](OC1)C(N)=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound