Milademetan tosylate hydrate - CAS 2095625-97-9

Milademetan (DS-3032) tosylate hydrate, an orally active and specific MDM2 inhibitor, is utilized in the study of acute myeloid leukemia (AML) and solid tumors. It induces G1 cell cycle arrest, senescence, and apoptosis, showcasing its therapeutic potential [1] [2].

Others, Apoptosis, E1/E2/E3 Enzyme, MDM-2/p53

Others, Ubiquitination, Apoptosis

2095519

C37H44Cl2FN5O8S

808.74

S(=O)(=O)(O)C1=CC=C(C)C=C1.O=C1[C@@]2(C3(N[C@@H](C(N[C@@H]4CC[C@@H](C(N)=O)OC4)=O)[C@@H]2C=5C(F)=C(Cl)N=CC5)CCC(C)(C)CC3)C=6C(N1)=CC(Cl)=CC6.O

-20°C

Ice Packs

Small Compound