MIND4-17 - CAS 345989-24-4

MIND4-17, a potent NRF2 activator, covalently modifies the C151 residue of Keap1, disrupting the Keap1-Nrf2 association. This action leads to the stabilization and nuclear translocation of the Nrf2 protein, consequently exerting potent antioxidant activity.

Nrf2, Others

Immunology/Inflammation, Others

345961

C20H15N5O3S

405.43

S(C=1N(C(COC2=CC=CC=C2)=NN1)C3=CC=CC=C3)C4=CC=C(N(=O)=O)C=N4

-20°C

Ice Packs

Small Compound