Molfinity
Minnelide free acid - CAS 1254885-39-6
Minnelide free acid - CAS 1254885-39-6
SKU:MF-0145376-01
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Product Details
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Bioactivity
Minnelide is an effective therapy against pancreatic cancer. Minnelide Inhibits Androgen Dependent, Castration Resistant Prostate Cancer Growth by Decreasing Expression of Androgen Receptor Full Length and Splice Variants. Minnelide reduced tumor volume in multiple models of pancreatic cancer. Minnelide was a more effective drug against pancreatic cancer models. It effectively reduced tumor burden and tumor related morbidity in different unique but complementary mouse models. It reduced metastatic spread and increased survival in the different models as well.
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Target
Apoptosis, Others
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Related Pathways
Apoptosis, Others
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CAS Number
1254840
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Molecular Formula
C21H27O10P
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Molecular Weight
470.41
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SMILES
C[C@@]12[C@@]34[C@]5([C@H](OCOP(=O)(O)O)[C@]6(C(C)C)[C@]([C@@]3(O4)[H])(O6)[H])[C@@](O5)(C[C@]1(C7=C(CC2)C(=O)OC7)[H])[H]
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound