Minocycline - CAS 10118-90-8

Minocycline is a broad-spectrum and highly lipophilic tetracycline antibiotic with the advantages of being orally administrable and able to penetrate the blood-brain barrier. It binds to the 30S ribosomal subunit to inhibit protein synthesis, is effective against both Gram-positive and Gram-negative bacteria, and also has neuroprotective, anti-inflammatory, and antioxidant effects.

Potassium Channel, ribosome, Calcium Channel, Apoptosis, Antioxidant, MDM-2/p53, HIF/HIF Prolyl-Hydroxylase, ROS, Antibiotic, Antibacterial

Immunology/Inflammation, Microbiology/Virology, Membrane transporter/Ion channel, Chromatin/Epigenetic, Oxidation-Reduction, Metabolism, Apoptosis

10118-90-8

C23H27N3O7

457.48

O[C@]12[C@]([C@H](N(C)C)C(O)=C(C(N)=O)C1=O)(C[C@]3(C(=C2O)C(=O)C=4C(C3)=C(N(C)C)C=CC4O)[H])[H]

-20°C

Ice Packs

Small Compound