MIPS-9922 - CAS 1416956-33-6

MIPS-9922 is a potent and selective PI3Kβ inhibitor with antiplatelet activity. MIPS-9922 inhibited integrin αIIbβ3 activation and αIIbβ3 dependent platelet adhesion to immobilized vWF under high shear. MIPS-9922 also potently inhibited ADP-induced washed platelet aggregation.

Others, PI3K

Others, PI3K/Akt/mTOR signaling

1416956-33-6

C28H31F2N9O2

563.6

C(F)(F)C=1N(C=2C(N1)=CC=CC2)C=3N=C(N=C(N3)N4CCOCC4)N5CCN(C([C@H](CC6=CC=CC=C6)N)=O)CC5

-20°C

Ice Packs

Small Compound