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MIR002 - CAS 2217671-64-0
MIR002 - CAS 2217671-64-0
SKU:MF-0140036-01
Regular price
$1,927.85 USD
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$1,927.85 USD
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Product Details
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Bioactivity
MIR002 is a potent, orally active dual inhibitor of DNA polymerase α (POLA1) and HDAC 11 with significant in vivo antitumor activity. p53 acetylation, p21 activation, cell cycle arrest in G1/S phase, and apoptosis induction.
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Target
Apoptosis, DNA/RNA Synthesis, Others, HDAC
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Related Pathways
Chromatin/Epigenetic, Cell Cycle/Checkpoint, Apoptosis, DNA Damage/DNA Repair, Others
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CAS Number
2217607
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Molecular Formula
C27H29NO5
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Molecular Weight
447.52
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SMILES
O(CC(NO)=O)C1=C(C23CC4CC(C2)CC(C3)C4)C=C(C=C1)C5=CC=C(/C=C/C(O)=O)C=C5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound