Mitoguazone - CAS 459-86-9

Mitoguazone (Methyl-GAG) is a selective S-adenosyl-methionine decarboxylase inhibitor that penetrates the blood-brain barrier and disrupts polyamine biosynthesis. Mitoguazone is a synthetic polycarbonyl derivative with anti-tumor activity that inhibits the integration of HIV DNA into cellular DNA in monocytes and macrophages, inducing apoptosis. Mitoguazone can be used to prevent acute leukemia, Hodgkin lymphoma and non-Hodgkin lymphoma.

Apoptosis, HIV Protease

Apoptosis, Microbiology/Virology, Proteases/Proteasome

364

0.98

C5H12N8

184.2

C\C(\C=N\NC(N)=N)=N/NC(N)=N

-20°C

Ice Packs

Small Compound