Molfinity
MitoPeDPP - CAS 1187472-58-7
MitoPeDPP - CAS 1187472-58-7
SKU:MF-0115591-01
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Product Details
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Bioactivity
MitoPeDPP serves as a cell-permeable fluorescent probe used to detect mitochondrial lipid peroxides. It exhibits selectivity for tert-butyl hydroperoxide (t-BHP) rather than hydrogen peroxide, superoxide, nitric oxide, or peroxynitrite. When oxidized by lipid peroxides, MitoPeDPP emits fluorescence at 470 nm when excited at 452 nm. Monitoring lipid peroxidation is crucial for understanding numerous cellular processes, particularly ferroptosis, an iron-dependent cell death marked by heightened lipid peroxidation.
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Target
Others
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Related Pathways
Others
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CAS Number
1187407
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Molecular Formula
C53H41IOP2
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Molecular Weight
882.74
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SMILES
[I-].O(C1=CC=C(C=C1)P(C=2C=CC=CC2)C3=CC=C4C5=CC=CC=6C=CC=C(C7=CC=CC3=C74)C65)CCC[P+](C=8C=CC=CC8)(C=9C=CC=CC9)C=%10C=CC=CC%10
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Dye-Reagents