Mitoxantrone diacetate - CAS 70711-41-0

Mitoxantrone diacetate is a potent inhibitor of topoisomerase II. Mitoxantrone diacetate also inhibits protein kinase C (PKC) (IC50: 8.5 μM) . Mitoxantrone diacetate exhibits antitumour effects and also has an antiorthopoxvirus effect, acting against bovine pox (EC50: 0.25 μM) and monkey pox (EC50: 0.8 μM) .

Others, Endogenous Metabolite, PKC, Apoptosis, Topoisomerase, Virus Protease

Metabolism, Chromatin/Epigenetic, Apoptosis, Others, DNA Damage/DNA Repair, Cytoskeletal Signaling, Microbiology/Virology

70670

C26H36N4O10

564.592

CC(O)=O.CC(O)=O.OCCNCCNc1ccc(NCCNCCO)c2C(=O)c3c(O)ccc(O)c3C(=O)c12

-20°C

Ice Packs

Small Compound