MK-0626 - CAS 690257-74-0

MK-0626 is an orally available dipeptidyl peptidase IV (DPP-4) inhibitor that attenuates hepatic steatosis and accumulation by enhancing AMPK activity.MK-0626 attenuates TAC-induced diabetic pancreatic islet injury by restoring the expression of GLP-1R.MK-0626 is able to increase circulating endothelial progenitor cell numbers and endothelial-type nitric oxide synthase expression by promoting neoangiogenesis.

Glucagon Receptor, AMPK

GPCR/G Protein, PI3K/Akt/mTOR signaling, Chromatin/Epigenetic

690183

>99.99%

C22H24F2N6O2

442.46

[C@H]([C@@H](C(=O)N1CC(F)(F)CC1)N)(C(N(C)C)=O)C2=CC=C(C=C2)C3=CN4C(C=C3)=NC=N4

-20°C

Ice Packs

Small Compound