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MK-1468 - CAS 2769107-89-1
MK-1468 - CAS 2769107-89-1
SKU:MF-0159050-01
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Product Details
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Bioactivity
MK-1468, a highly selective and brain-penetrant LRRK2 inhibitor, exhibits an IC50 of 0.8 nM and is utilized in the study of Parkinson's disease [1].
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Target
LRRK2
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Related Pathways
Autophagy
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CAS Number
2769107-89-1
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Molecular Formula
C26H33ClN4O4
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Molecular Weight
501.02
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SMILES
C(NC1=CC2=C(C=N1)C=C(Cl)C(=C2)N3CCN(CC3)[C@@]4(C)[C@@H](O)COC4)(=O)[C@@H]5C6(C5)CCOCC6
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound