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MK-2206 - CAS 1032349-77-1

MK-2206 - CAS 1032349-77-1

MF-0036782-01

$1,927.85 USD
$1,391.00 USD $1,927.85 USD
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Product Details

  • Bioactivity

    MK-2206 is an orally active, highly selective, metabotropic Akt inhibitor that targets Akt1 [IC50: 8 nM], Akt2 [IC50: 12 nM], and Akt3 [IC50: 65 nM]. Many breast cancer cell lines, PIK3CA mutants, and PTEN-losing cell lines are sensitive to MK-2206, which exhibits anti-cancer effects.

  • Target

    Akt, Apoptosis, Autophagy, Others

  • Related Pathways

    PI3K/Akt/mTOR signaling, Others, Autophagy, Cytoskeletal Signaling, Apoptosis

  • CAS Number

    1032349-77-1

  • Molecular Formula

    C25H22ClN5O

  • Molecular Weight

    443.94

  • SMILES

    Cl.NC1(CCC1)c1ccc(cc1)-c1nc2ccn3c(n[nH]c3=O)c2cc1-c1ccccc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound