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MK-8033 hydrochloride - CAS 1283000-43-0

MK-8033 hydrochloride - CAS 1283000-43-0

MF-0006178-01

$971.38 USD
$682.50 USD $971.38 USD
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Product Details

  • Bioactivity

    MK-8033 hydrochloride is an effective and orally active dual inhibitor of ATP competitive c-Met/Ron, with 1 nM for c-Met and 7nM for Ron IC50. MK-8033 hydrochloride has a high affinity for activated kinase conformation, and is suitable for the study of breast cancer, bladder cancer, and non-small cell lung cancer (NSCLC) .

  • Target

    C-Met/HGFR, Others

  • Related Pathways

    Tyrosine Kinase/Adaptors, Others

  • CAS Number

    1283000-43-0

  • Molecular Formula

    C25H22ClN5O3S

  • Molecular Weight

    507.99

  • SMILES

    Cl.Cn1cc(cn1)-c1cnc2ccc3ccc(CS(=O)(=O)NCc4ccccn4)cc3c(=O)c2c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound