Molfinity

MK-8153 - CAS 1548286-45-8

SKU:MF-0092977-01

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Product Details

Bioactivity
MK-8153 is a selective, potent, orally active inhibitor of extrarenal medullary potassium channels (ROMK), acting on ROMK EP (IC50: 5 μM) and hERG EP (IC50: 34 μM) .MK-8153 can be used as a diuretic.
Target
Others, Potassium Channel
Related Pathways
Membrane transporter/Ion channel, Others
CAS Number
1548233
Molecular Formula
C24H28N2O6
Molecular Weight
440.49
SMILES
O=C1C2(CCN1C3=C(C)C(=O)OC3)CCN(C[C@H](O)C=4C(C)=C5C(=CC4)C(=O)OC5)CC2
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound