Molfinity

MK-8617 - CAS 1187990-87-9

SKU:MF-0046159-01

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Product Details

Bioactivity
MK-8617 is an orally available HIF PHD1 3 pan-inhibitor, inhibiting PHD1/2/3 (IC50: 1.0/1.0/14 nM) .
Target
HIF/HIF Prolyl-Hydroxylase
Related Pathways
Chromatin/Epigenetic, Metabolism
CAS Number
1187894
Purity
>99.99%
Molecular Formula
C24H21N5O4
Molecular Weight
443.45
SMILES
COc1ccc(cc1)C(NC(=O)c1cnc([nH]c1=O)-c1cccnn1)c1ccc(OC)cc1
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound