MK-8666 Tris - CAS 2056254-98-7

MK-8666 Tris is a partial GPCR (G-protein-coupled receptor) agonist that is coordinated with the action of GPR40. GPR40, also known as free fatty acid (FFA) receptor 1 modulates fatty acid-induced insulin secretion in pancreatic beta cells and in intestinal enteroendocrine cells. Thus, MK-8666 Tris has been investigated for treatment of type 2 diabetes mellitus and has been shown to robustly lower glucose without negative effects.

Others, GPCR

GPCR/G Protein, Others, Endocrinology/Hormones

2056149

C33H42N2O9S

642.764

NC(CO)(CO)CO.[H][C@@]12Cc3cc(OCc4cccc(c4)-c4c(C)cc(OCCCS(C)(=O)=O)cc4C)ncc3[C@]1([H])[C@H]2C(O)=O

-20°C

Ice Packs

Small Compound