Molfinity

MK-8768 - CAS 1432729-22-0

SKU:MF-0157140-01

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Size 5 mg 50 mg

Product Details

Bioactivity
MK-8768 is a potent, selective, and orally bioavailable negative allosteric modulator of the mGluR2 class, exhibiting an IC50 of 9.6 nM and characterized by excellent brain permeability.
Target
Others, GluR
Related Pathways
Others, Neuroscience
CAS Number
1432707
Molecular Formula
C21H22F3N5O2
Molecular Weight
433.43
SMILES
C(N)(=O)C=1C=C(C2=C(C=C(CN3C[C@H](C(F)(F)F)O[C@H](C)C3)C=C2)N1)C4=CN(C)N=C4
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound