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MKC-1 - CAS 125313-92-0

MKC-1 - CAS 125313-92-0

MF-0017181-01

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Product Details

  • Bioactivity

    MKC-1 (Ro-31-7453) is an orally bioavailable small-molecule bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its metabolites inhibit tubulin polymerization, blocking mitotic spindle formation, which may result in apoptosis and tumor cell death.

  • Target

    Microtubule Associated, Akt, Apoptosis, mTOR

  • Related Pathways

    Cytoskeletal Signaling, Apoptosis, PI3K/Akt/mTOR signaling

  • CAS Number

    125221

  • Purity

    0.9985

  • Molecular Formula

    C22H16N4O4

  • Molecular Weight

    400.39

  • SMILES

    Cn1cc(C2=C(C(=O)NC2=O)c2cn(C)c3cc(ccc23)[N+]([O-])=O)c2ccccc12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound