MKLP2-IN-1 - CAS 2929345-46-8

MKLP2-IN-1 (compound 12a) is an inhibitor of MKLP2 that demonstrates excellent oral bioactivity. In vitro, MKLP2-IN-1 inhibits the ATPase activity stimulated by recombinant MKLP2 microtubules and, in a mouse Calu-6 lung cancer model, it effectively suppresses tumor growth.

Kinesin

Cytoskeletal Signaling

2929291

C23H19BrFN3O2

468.318

O=C1N(C=2C=CC=CC2C(Br)=C(C3=NN=C(O3)C4CC4)C1)CC5=CC=C(C(F)=C5)C

-20°C

Ice Packs

Small Compound