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ML 120B dihydrochloride - CAS 1782573-78-7
ML 120B dihydrochloride - CAS 1782573-78-7
SKU:MF-0045935
Regular price
$96.50 USD
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$96.50 USD
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Product Details
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Bioactivity
MLN120B dihydrochloride (ML120B dihydrochloride) is a highly potent, orally active inhibitor of IKKβ, competitively binding to ATP with an IC50 value of 60 nM, effectively suppressing the growth of multiple myeloma cells in vitro and in vivo, and valuable in rheumatoid arthritis research.
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Target
Others, IκB/IKK
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Related Pathways
NF-κB, Others
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CAS Number
1782488
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Molecular Formula
C19H17Cl3N4O2
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Molecular Weight
439.72
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SMILES
Cl.Cl.COc1c(Cl)cc2c3ccncc3[nH]c2c1NC(=O)c1cccnc1C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound