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ML-309 (hydrochloride) - CAS 1355327-02-4

ML-309 (hydrochloride) - CAS 1355327-02-4

MF-0006763-01

$140.38 USD
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Product Details

  • Bioactivity

    ML-309 is an inhibitor of mutant isocitrate dehydrogenase 1 (IDH1) . It reversibly and selective inhibits IDH1R132H over wild-type IDH1 (IC50s = 96 and 36,500 nM, respectively) . ML-309 reduces 2-hydroxyglutarate production in U87 MG glioblastoma cells (EC50 = 55 nM) .

  • Target

    Others

  • Related Pathways

    Others

  • CAS Number

    1355327-02-4

  • Molecular Formula

    C29H30ClFN4O2

  • Molecular Weight

    521.03

  • SMILES

    Cl.Cc1ccccc1C(N(C(=O)Cn1cnc2ccccc12)c1cccc(F)c1)C(=O)NC1CCCC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound